Perrigo Diphenhydramine HCL and Zinc Acetate Itch Relief Cream Relieves skin irritation and itching immediately.Topical analgesic and skin protectant that provides effective temporary relievef of pain and itching associated with insect bites, rashes, skin irritation from poison ivy, poison oak, and poison sumac.Also eases the pain and itching of minor burns, sunburn, windburn and scraps.Rapid, soothing relief.