Dulcolax stool softener laxatives provide gentle constipation relief by softening painful, hard, dry stools in 12 to 72 hours. Made with docusate sodium, the No. 1 doctor-recommended ingredient,* they work naturally with the water in your body to hydrate the stool, making it easier to pass. Keep Dulcolax stool softeners on hand for on-the-go constipation relief.