Vicks DayQuil Cold & Flu provides powerful, non-drowsy, daytime relief for your worst cold and flu symptoms. DayQuil relieves headache, fever, sore throat, minor aches & pains, nasal congestion, and cough. Contains acetaminophen. Vicks NyQuil Cold & Flu gives powerful nighttime relief for your worst cold and flu symptoms so that you can get the rest you need. Fight symptoms such as cough, headache, fever, sore throat, minor aches and pains, sneezing, runny nose. Contains acetaminophen. Use as directed. Keep out of reach of children. Data represents brand/product selections from the 2020 Pharmacy Times Survey of Pharmacists' OTC Recommendations.