Get all-day heartburn relief with Zegerid Heartburn Capsules. Zegerid OTC capsules have a unique, dual-ingredient formula, containing the leading prescription acid-reducer (omeprazole) and the antacid sodium bicarbonate, which protects this effective medicine from the acid in your stomach, allowing it to be absorbed. The omeprazole found in Zegerid is a Proton Pump Inhibitor (PPI), which is the only medicine specifically indicated to treat frequent heartburn. Just one capsule provides 24-hours of relief from frequent heartburn by blocking the production of acid that causes it. If you're looking for longer rather than short-lived relief, try Zegerid to treat your frequent heartburn. When stomach acid backs up into your esophagus causing heartburn, turn to Zegerid OTC. *Use as directed for 14 days for treating frequent heartburn. Zegerid OTC may take 1-4 days for full effect, although some people get relief within 24 hours.